Acupuncture exerts post-operative anti-inflammatory responses thereby preventing abdominal adhesions. Published in the Journal of Surgical Research, investigators have discovered a major biological mechanism that may be responsible for these beneficial effects. The research team concludes, “EA (electroacupuncture) ST36 might reduce the postoperative local inflammatory response, attenuate the angiogenesis and alleviate the adhesion formation partly via activating the cholinergic anti-inflammatory mechanism.”
Histopathological and macroscopic evaluations confirm that electroacupuncture at ST36 reduces post-operative adhesion formation. In addition, the researchers note that electroacupuncture at ST36 “significantly decreased angiogenesis evidenced by reduced CD31 positive microvessel density (MVD) in adhesive tissue.” CD31 (Cluster of Differentiation) is a protein that regulates neutrophil removal and expresses in vascular tumors, sarcomas and carcinomas.
Related research confirms the anti-inflammatory effects of acupuncture. Another recent study reveals that acupuncture at acupoints GV20 and GB7 regulates the cascade of endogenous inflammatory chemicals released after a stroke. These acupuncture points prevent inflammation by inhibiting IL-1beta in the brain tissue region of a hematoma. IL-1beta is a pro-inflammatory cytokine, a cell-signaling protein molecule used in intercellular communication.
Scalp acupuncture causes a rapid decrease of IL-6 (Interleukin-6), another cytokine involved in the inflammatory response. Left unchecked, IL-6’s pro-inflammatory effects are pathological. IL-6 mediates fevers, crosses the blood-brain barrier and is found in high levels in patients with metastatic cancer.
The researchers note that acupuncture at GV20 and Taiyang has an “inhibitory effect on the immune-inflammatory reaction mediated by TNF-(alpha) expression….” Additionally, acupuncture at GV20 and GB7 “promoted heat shock protein 70 (HSP70) mRNA expression in brain tissue….” HSP70 helps cells fold proteins and have the ability to protect cells from stress. Other scalp acupuncture research shows “improved mitochondrial energy metabolism in (the) brain….”
Neuro-electrophysiology scalp acupuncture studies show that acupuncture at GV20 and Taiyang improves “coordination and compensation functions among cortical functional areas” in ICH patients. Scalp acupuncture has also been shown to beneficially affect the electrical activity of pain reaction neurons. Also noted, GV20 and GB7 promote the expression of glial cell neurotrophic factor GDNF, a protein that promotes the survival of neurons.
Du, Ming-Hua, Hong-Min Luo, Yi-Jun Tian, Li-Jian Zhang, Zeng-Kai Zhao, Yi Lv, Rui-Jiang Xu, and Sen Hu. “EA ST36 prevents postoperative intra-abdominal adhesions formation.” Journal of Surgical Research (2014).
Evidence-Based Complementary and Alternative MedicineVolume 2012 (2012), Article ID 895032, 9 pages. doi:10.1155/2012/895032.
History and Mechanism for Treatment of Intracerebral Hemorrhage with Scalp Acupuncture. Zhe Liu, Ling Guan, Yan Wang, Cheng-Long Xie, Xian-Ming Lin and Guo-Qing Zheng. The Third Clinical College of Zhejiang Chinese Medical University, Hangzhou. Department of Acupuncture and Moxibustion, General Hospital, Beijing. Center of Neurology and Rehabilitation, The Second Affiliated Hospital of Wenzhou Medical College, Wenzhou.